League Record: Jim Taylor, DUB – 254 yards.
Most Games: Jim Brown, RIO – 10.
| PLAYER | TEAM | GAMES | HIGH |
|---|---|---|---|
| Marshall Faulk | LOM | 6 | 286 |
| LaDainian Tomlinson | AAA | 10 | 240 |
| Franco Harris | IST | 4 | 204 |
| Jim Brown | RIO | 9 | 193 |
| Barry Sanders | AMS | 5 | 187 |
| Tiki Barber | NYG | 6 | 184 |
| Frank Gore | SFO | 5 | 179 |
| C.J. Anderson | TOK | 1 | 170 |
| Adrian Peterson | CTO | 9 | 169 |
| Edgerrin James | ROM | 6 | 168 |
| Jim Taylor | DUB | 9 | 166 |
| Emmitt Smith | LON | 1 | 162 |
| Chris Ivory | BOS | 3 | 155 |
| Wilbert Montgomery | SYD | 5 | 154 |
| Doc Elliott | RIO | 2 | 150 |
| Cliff Battles | BEI | 1 | 140 |
| Marshawn Lynch | LON | 5 | 129 |
| Jamaal Charles | RIO | 3 | 126 |
| LeSean McCoy | SYD | 1 | 126 |
| Alfred Morris | BEI | 1 | 123 |
| Warrick Dunn | BEI | 1 | 122 |
| Cam Newton | AMS | 1 | 120 |
| Walter Payton | BER | 2 | 107 |